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Intervention to reduce unnecessary antibiotic use in children in Zhejiang Province, China

china-hesketh

Project SummaryÌý

Antibiotic resistance (ABR) has been identified as one of theÌýgreatest threats to global population health this century, asÌýwell as a major contributor to rising healthcare costsÌýworldwide. The primary cause of ABR is antibiotic misuse,Ìýespecially the routine inappropriate use of antibiotics for self-limiting illnesses. Therefore, reducing antibiotic misuse hasÌýbecome an urgent priority, especially in low and middle incomeÌýcounties (LMIC) where systems to regulate antibiotic use areÌýweak or non-existent .Ìý

China has very high rates of ABR in both hospital andÌýcommunity-acquired infections, following decades of highÌýutilisation of antibiotics. The very large and mobile populationÌýalso increases the risk of spread of resistance. ÌýAround two-thirds of in-patients and 50-60% of out-patients are prescribedÌýantibiotics. ÌýAs elsewhere, the reasons for overprescribing ofÌýantibiotics in China are multifactorial, and therefore demand aÌýmulti-facetted response. Ìý

The overall aim of the project is to pilot an intervention toÌýreduce inappropriate antibiotic use in children in threeÌýtownships in Jiangshan County, Zhejiang Province through aÌýcontrolled community intervention. The methods compriseÌýdevelopment of guidelines for management of common self-limiting childhood, training of doctors in the use of theÌýguidelines, institution of a routine surveillance system forÌýantibiotic prescribing of all clinicians, with adherence toÌýprescribing guidelines contributing to performance-relatedÌýpay, and a community-based health education programme toÌýraise awareness about ABR.

Mid-term evaluation has shownÌýthat the project has succeeded in reducing antibioticÌýprescribing in intervention townships from 59% to 36%. ThisÌýsmall project also brought about improvements inÌýmanagement practices, clinician training, use of informationÌýsystems, prescribing patterns (beyond just antibiotics), hospitalÌýand doctors' accountability, doctor-patient communication, andÌýperceived overall quality of care.


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