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PhD Project Title:听Triglycerides, triglyceride containing lipoproteins and cardiovascular disease: causal relevance and potential therapeutic targets.
Supervisors:听Professor Aroon Hingorani
Lay summary:
Atherosclerosis is the build-up of fat and inflammatory material in the walls of blood vessels, a process which can lead to blockage of blood vessels which underlies conditions such as heart attacks and stroke. High levels of low-density lipoprotein cholesterol (LDL-C), a particular type of fat circulating in the blood is a definite cause of atherosclerosis. However, it is unclear whether other circulating fats, such as those containing triglycerides are also involved in atherosclerosis disease progression.听
I aim to confirm or refute the causal role of triglycerides in heart disease and stroke using state-of-the art omics tools in a population genetic approach.听
笔耻产濒颈肠补迟颈辞苍蝉听
Contact details听
Roshni.joshi.16@ucl.ac.uk
Twitter: @roshnijoshi
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