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Study provides new insights into the genetic architecture and pathogenesis of heart failure

5 February 2020

image of heart

Heart failure is a complex syndrome for which the causal basis is incompletely understood. Here, the authors perform a genome-wide association study and identify 11 loci, ten had not been previously reported, and appraise the aetiological contribution of observationally associated risk factors through Mendelian randomisation analysis.

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